vol2 - Page 47

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 the nervous system which is affected and according to the severity of the disease°
 The symptoms can include one or more of the following: weakness, tingling,
 numbness, impaired sensation, lack of coordinations, disturbances in equilibrium,
 double vision, loss of vision, involuntary rapid movement of the eyes (nystag_s),
 slurred speech, tremors, stiffness, spasticity, weakness of limbs, sexual dysfunc_
 tion, para_ysls, and impaired bladder and bowel fu_ctionso
 4. Each person aff_i_ed by n_]tlple sclerosis is af?ected different]yo
 In some persons_ the s.ympto_ o_ the disease are barely detectable, even over
 long periods of t_me. In these cases, the persons can 1_ve their lives as if
 they did not suffer from the disease° %n others, more of the symptoms are present.
 ": and acute, thereby limiting their physical capabilities° Moreover, others may
 experience sporadic, but acute, symptoms.
 5. At this time, there is no known prevetntion or cure for multiple
 ..... sclerosis. Instead, there are onloy treatments for the symptoms of the disease.
 There are very few drugs specifically designed to treat spasticlty. These drugs
 often cause very serious side effects. At the present ti_e two drugs are
 approved by FDA as =safe" and %ffective" for the specific indication of
 spasticity. These drugs are Dantriu_ and Llor_sal baclofen.
 6. Unfortunately_ nelther Dantriu_ nor L1oresal is a very effective
 spasm coB_ro'l drug. The'St _arglnal _edical _._Ii_y, high toxicity and potential
 .... 7. As a result, _any physicians routinely prescribe tranquilizers,
 _scle re_axani:$, mood e'lev_tors and sedatives such a_ Valiu_ to patients
 experiencing spasticityo _hile these drugs do not directly reduce spasticity

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