vol2 - Page 344

 9-85
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 amount of testing that was done with this materiai_
 as I say_ it wasn't until one starts to see seven
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 ...... million prescriptions written per year that you start
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 to _ee these things_ Once they were recognized as
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 adverse effects, and I this historically certainly=-
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 if you have this same manuscript and you're citing
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 -- from here _- then one can see that in the first--
 S
 act_a°!ly 1978 was not good. because it was only
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 reached in September_ but lefts say four years of its
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 release. The number of adverse effects were
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 substantial e quite high, but then they dropped off to
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 ten percent of the normal.
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 Again_ I think once the warnlnq label
 14 showed that you shouidn_t use this material in these
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 types or different types of patients_ Then one is
 16 much more aware of the experiences of others in terms
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 of reporting these adverse effects°
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 Anyhow, ! would just be cognizant of the
 \
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 fact that the adverse effect numbers have dropped.
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 off.
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 But one thlng that you're sayings Z guess,
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 is that doctors have been able to make a rlsk-benefit
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 decision for an individual patient and determine
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 whether or not this dz_/g is appropriate°
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 Well, if the patient; has no predisposing
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