vol2 - Page 264

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 __- 12. The adverse physical consequences resulting from
 the chronic use of systemic glaucoma control drugs include a
 vast range of unintended complications from mild problems like
 drug induced fevers_ skin rashes, headaches, anorexia_ asthma,
 pulmonary difficultiess hypertension, hypotension and muscle
 cramps to truly serious_ even life-threatening complications
 including the formation o_ cata_actss stomach and intestinil
 ulcers_ acute respiratory distress_ increases and decreases in
 heart rate and pulses disruption of heart functions chronic and
 acute renal disease, and bone marrow depletion.
 13. Finally, this partial listing must also include
 a candid recognition that each drug family used in glaucoma
 therapy is capable of producing a lethal responsep even when
 _ properly prescribed _nd uSedo Epinephrine can lead to elevated
 blood pressure which may result in stroke or heart attack.
 Miotic drugs suppress respiration and can cause respiratory
 paralysis_ Diuretic drugs so alter basic body chemistry they
 cause renal stones and may destroy the patient's kidneys or
 result in death due to heart failu=eo Timolol and related
 beta-blocking agentss the most recently "approved _ family of
 glaucoma control drugs_ can trigger severe asthma attacks or
 cause death due to sudden cardiac arrhyt_ias often producing
 14. Ca_bonlc Anhydrase Inhibitors - Diamox
 !. Metabolic acids persJ_stent hypokalemia
 dehydrations loss of appetite.§ lethargy accompany maximum
 p therapy (250 mg QID or 500 m s BXD) in the United States°

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