vol2 - Page 219
Page 219
Previous ,
Next ,
Original Image
Return to Index
receiving marijuana as an adjunct to their chemotherapy
treatments.
71. Efforts to track down the reason for this response
have proved inconclusive° Initially, we felt that these
patients, two of whom were naive smokers, might not be properly
kitrating themselve_o Marijuana, because it is _nhaled, allows
patients to exercise considerable control over the delivery of
a dose. Rowever, naive smokers, lacking prior experiences
might be inhaling too much synthetic Delta=9 THC and/or other
chemicals° This mini_overdose possibly triggered the collapse
in blood pressure°
72. Serum Deltas9 THC levels failed to correlate with
orthostatic hypotension in the three subjects 9ncountered.
....... 73° This orthostatic hypotensive response may be more
likely in patients with essential hypertension and glaucoma.
In all subjects, this response is abated within ten to fifteen
minutes by assuming a reclining position°
74. Determining what drugs are appropriate within the
context of medical therapy is a constant balancing of benefits
and risks. All of the drugs employed in glaucoma control
therapies have serious adverse effects.
75. In a recent review of Timolol's use over the past
eight years in glaucoma therapy_ a recent journal article noted
i that thirty-two deaths have been attributed to Timolol's use in
glaucoma therapy_ reported up to 1986_
76° Similarly, all of the other drugs employed for IOP
reduction can have serlous_ even llfe-threatening adverse
Previous ,
Next ,
Return to Index