vol2 - Page 175
Page 175
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19o Cancer patients who receive chemotherapy go through
an almost Pavlovian cycle of response. If they vomit after
their first chemotherapy sessions they become more apprehensive
about the second treatment. During the second treatment the
vomiting is likely to start sooner and be more severeŽ The
patient becomes more and more terrified of the therapy and this
sense of terror, and lack of controls serves to intensify the
adverse reaction. In a short period of timew patients become
so conditioned they may actually begin to vomit on the way to
the hospital for their therapy_
20. Unfortunately, there are very few effective anti-
emetic drugs available to these patients. Compazine, the stan-
dard anti-emetic in use during the late 1970's and early
1980's, seldom affords patients with any reliable relief from
the nausea and vomiting caused by the use of chemotherapeutic
agents. Some estimates suggest fewer than twenty percent of
vomiting patients find Compazine helpful_
21. In 1976, while a Georgetown Fellow in Medical
Oncology, _ was seeking to find ways to improve the quality of
patient care within a supportive environment. As part of my
review of materials, I investigated the role of nutrition and
diet, evaluated the possibility of using hypnosis, and explored
the use of other drugs which might help to stem the
debilitating nausea and vomiting these cancer patients
experienced.
22. My. objective was to break the cycle of vomiting by
preventing or reducing the amount of vomiting, the number of
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