vol1 - Page 326
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[I]ntroduction of a drug into the body by..
smoking is a very efficient method of
administration .... Persons who have
recreationally smoked marijuana, who know how
to titrate themselves, would probably have
little difficulty in
emck_ the drug for
medical treatment ....
Many witnesses have testified that patients exercise
very fine control overthe i_nalation of marijuana. _-_/ This
fact haml be_n demonstrated in numerous studieso _/ While DEA and
other federal agencies promoted a _standardized smoking x regimen_
the state-authorized treatment programs quickly abandoned this
inflexible approach. Georgia found patients compelled to smoke
in a rigid, pre-determined or Nstandardized" way were less
likely to benefit from the therapy. _-Q/ Both New York and
California first adopted the govelnlment_s _standardized smoking _
regimen, then abandoned this approach and altered their INDs to
permit patient _self-titrationo w_ul/
__Z/ Affidavit of Raphael Mechoulam_ Ph.D., _ 12.
_/ ACT Brief at i08, 109.
49/ Cross-examination of Dr. Norman Zinberg Tr° 11-199-203o
Drs. Sallan and Zinberg found patients abandoned their 1974_75
oral THC study to smoke marijuana because it was more con-
trollable. Affidavit of Dr. Norman Zinberg, Exhibit 3; Cross
Examination of Madelyn Brazis, R.N. Tr. 7-212 Affidavit of Rona_
Stephens_ _ 17; Cross=examination of Dr. J_ Thomas Ungerleider_
Tr. 4-117; $e9_ al_ ACT Brief at 108-09.
__q/ ACT Official State Reports_ Vol_ II_ Exhibit 8 at Table 2 =
C. See _il_q ACT Brief at 57.
51/ ACT Official State Reports, VOlo iI_ Exhibit 16. Governor
and Legislature on the Antonio G. Olivieri Controlled Substances
Therapeutic Research Program, September i, 1982, at 5. See_!l__2
ACT Brief at 71.
The Consensus among experienced investigators
[is] that patients should smoke [marijuana]
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