vol1 - Page 299
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. five thousand years of u_e® _-D-4-/ Second, the therapeutic index of
marijuana is very high and thus the drug is quite safe. °705/ The
drug Ss safety is further enhanced by the fact that patients
suffering from spasticity gain reliefafter smoking only small
amounts of the drugs-probably only a single cigarette a day. _9-_/
By contrasts he noted, drugs such as Vellum, Dantrium and
Lioreeal have very low therapeutic indices. _-Q7/ Finaily_ Dr.
Petro stated that marijuana reasonably could be considered as
safe as Marinol (dronabinol)--an FDA-approved drug. _9-_/
Regarding this matter, the Physicians" Desk Reference declares
NFor practical purposes_ the nontherapeutio effects of Dronabinol
may be considered essentially identical to those of marijuana and
other centrally active cannabinoids. _7--_-/ This language, Dr.
Petro testified, constitutes FDA-approved labeling for
Marinolo !l-q/ Based upohthis information_ Dr° Petro concluded_
marijuana Uvery definitely _ is safe _nder medical supervision for
the treatment of spasticity. _!-_/
7Q_/ He acknowledged that two deaths were reported in North
Africa during the early Nineteenth Century. These deaths_
however, were probably not due to marijuana ingestion but to
other complications. Cross-examination of Dro Denis Petro_ Tr.
6-148.
7Q_/ Id° at Tr° 6_i74 & 6-175o
7Q6/ /_. at 6-78.
7_/ /_ at 6-144 to 6_145_ 6_174o
708/ /_® at 6-182 to 6_183.
709./ /._. at 6-166.
71Q/ I_°
__Ii/ /_. at 6-186o
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