vol1 - Page 237
Page 237
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well tolerated by most patients_ There were, in fact,
surprisingly few adverse effects repo_:ed by _hese investigators,
and the majority of such reports occurred while patients were
employing synthetic THC pills, not inhalation marijuanas
-_ _hile numerous side effects {coughing/sore
throat, eto) are mmntioned_ none of the reports from medical
studies of marijuanaSs use in reducing emesis or lowering IOP
appear to involve clinically si_nificar_ adverse effects (i.eo,
d_age to major organ syste_ or other physically debilitating
consequences which render the patient non-functional or seriously
impaired).
-- One concern involves patient acceptance of the
therapy° Nhile no such data are available specific to
marijuana_s IOP !cwering properties, Michigan evaluated patient
acceptance and found that cancer patients often preferred
˘
marijuana to more conventional antiemetic drugs. 522/
_ The only cautionary note_ concerns marijuanaFs
..... _
potential affects on blood pressure as reported by Drs° John
Merritt and William Crawford. Merritt and Crawford report a
small number of patients given synthetic THC in oral form cannot
-_ tolerate the dz_/g_s intense, often negative psychic effects.
They also report synthetic THC and marijuana can cause a sudden_
sharp decline in blood pressure° _21_/
/
522/ ACT Official State Reports, Volume II, Exhibit 9, at I0_
Michigan Therapeutic Research Program.
52_/ ACT Scientific Journal Articles, Exhibit C9, Merritt, John
C., Crawford_ William J._ Alexander, Paul, Anduze, Alfred, L., &
Gelbart, Solomon S., #Effect of Marijuana on Intraocular and
(continued..°)
= 164 -
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