vol1 - Page 224
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demonstrated that marijuana and several of the plant's major
constituent chemicals significantly reduce intraocular pressure.
In I%70_ the University of California at Los Angeles
(UCLA) initiated a federally-approved study funded by the
National Institute on Mental Health (NIMH) to investigate
marijuana_s effects on various aspects of human physiology.
Studies conducted within the UCLA/Marijuana Research Project were
double blind, placebo controlled evaluationso 489/
The discovery that marijuana smoking significantly
reduces human intraocular pressure was made serendipitously by
researchers seeking to resolve a trivial question -_ the effect
of marijuanats smoking on pupil sizeo _/ Prior to the UCLA
studies, it was widely believed marijuana smoking caused the
pupils to dilate. The UCLA researchers set out to scientifically
answer this question. Ocular evaluations in the UCLA program
were performed by Dro Robert S. Hepler_ an ophthalmologist at the
Jules Stein Eye Institute. When Hepler evaluated the initial
results of the UCLA pupillary study he found marijuana did not
cause pupillary dilation. Instead, Dr. Hepler found marijuana
...... : ___/ ACT Official State Reports_ Volume IIs Exhibit I0, New
Jersey Glaucoma Protocol at 15.
%_Q/ ACT Scientific Journal Articles, Exhibit C2p Heplere Rober%
S. _ Frank, Ira Mo _ Ungerleider, J.To; _'l>_piliary Construction
After Marijuana Smoking, _ American Joux_nal of Ophthalmology, _
Vol. 74, No. 6 December, 1972, pp. 1185-90.
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