vol1 - Page 223
Page 223
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of glaucoma, but there are some adverse
side-effects. Some patients are refractory to
present forms of treatment and become blind
i_. as the disease progresses_ for them. there is
a Darticuiarlv urgent need_to f_in_ffective
_iL_. (Emphasis addedo) %_I
3_ Ma_uanats Therameutic Use in the Reduction of
l_-., In_Kaocul _; Pressure
-_ Well-controlled scientific studies and the experience
b
of glaucoma patients have demonstrated that marijuana, when
smoked, significantly reduces the elevated intraocular pressure
associated with qlaucomaŽ Xn addition, these studies -- as well
' as hundreds of additional, wide-ranging investigations _- show
marijuana can be safely used under medical supervision.
Marijuana_s IOP-lowering action was the first of the
drug's numerous therapeutic indications identified by contem-
.i_ porary physicians and quantified through modern scientific
evaluations. While marijuana_s IOP_lowering action was recog-
nized at the very beqinning of current _cesearch into cannabis
(1970), there appears to be no historical reference for this
therapeutic applicationo
Over the past eighteen years, numerous FDA-approved
_< investigators_ including Drs. Hepler, Ungerleider, Franks
Perez-Reyes, Green, Merritt, North and others have convincingly
!9__/ ACT Official State Reports, Exhibit i0 _at 14 - N.J.
Protocol (_otina Marijuana and Health, Report of a Study by a
Committee of the Institute of Medicine, National Academy of
.... Sciences, National Academy Press, Washinqton_ DoC., 1981 at 140).
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