vol1 - Page 182
Page 182
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effect, cessation of vomiting, occurs° This allows the patient
to maximize the benefit and minimize possible side effects. With
an oral medications titration is impossible and thus overdose is
more likelyo 36_/
Finally_ marijuana also presents some significant
advantages over several of the #newer _ intravenously administered
drugs used for treatment of emesis° Firsts there are practical
reasons° Marijuana is self-administrable by the patients_
themselves, whereas the Wnew_ antiemetics are most often given
intravenously. 3--_/ Aiso_ these new combinations require
hospitalization involving significant cost and time. Thusw they
are untenable and unrealistic to the current common practice of
oncology involving mostly out_patient treatment. _66/ It would be
_physically impossible x to administer these combinations in the
.context of an out-p_tient practiceo _-§-l/ Second, and most
significantly, there are humanitarian reasons° Hospitalization
of these patients for every different chemotherapy treatment may
take away a significant period of their remaining lifetime. Dr.
_./ Affidavit of Dr o Ronald Stephens, _ 17; Redirect of Dr o
Ronald Stephens, Tr. 2_!51. _ _ Affidavit of Dr. John
Morgan, _ 43 (titration prevents overdose situation)o Cross-
examination of Dro John Morgan, Tro 6_27_.3 (titration is common
form of administration--M, opioid narcotics, analgesics);
Redirect of Dr_ Ivan Silverberg, Tr. 3-151 (titration is a common
form of administration-_ioe___, anti-asthma drugs); Affidavit of
Madelyn Brazis, _ 56 (inhalation allows for extremely fine
manipulation of the dose)o
3_/ Redirect of Dr. John Bickers_ Tro 2-124.
36__6/ Cross-examination of Dr. !van Silverberg_ Tr. 3_127 & 3-
128 o
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