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 nstandardized # the methods by which patients smoked in order to
 nminimize the variation in the a_ount of smoke inhaledo "_2_/
 (b) "' _at
 As suggested above, the New York program involved
 _ several levels of controls. Prior to receiving marijuana within
 the New York programs a cancer patient had to fail to respond to
 one or two types of conventional antismetic therapy. 2_-_/ A
 second round of antiemetic therapy involving synthetic THC pills
 was often given to patients requesting admission into the
 inhalation programo 2_2_/ In effects these restrictions imposed
 severe historical controls on the patients who were finally
 admitted into New York's inhalation marijuana program. These
! historic controls also permit a comparative evaluation of the
 relative utility of conventional antiemetic therapies, synthetic
 THC and marijuanas
 In effect, the New York program set out to determine if
 ...... marijuanas when smoked_ could successfully reduce emesis in
 patients who have failed to respond to conventional agents and
 synthetic THC capsules. This aspect of the New York program is
 cemparable to the Chang/NCI study_s use of marijuana only after
 _21_/ /_o at 7_
 _28/ _o at 4_ (mA history of nausea and vomiting and failure
 of prior antiemetic therapy is required for enrollment in the
 protocol, n )
 _9/ ACT Official State Reports_ Vole XX_ Exhibit 16_ "Annual
 Report to the Governor and Legislature on the Antonio G. Olivieri
 Controlled Substances Therapeutic Research Program, # New York
 State Department of Healths September Is 1982_ at 4.
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