norml22 - Page 26
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Finally, in considering marijuana's low potential for abuse,
it is important to emphasize that it is virtually impossible to
consume a lethal dose of marijuana. See Exhibit A (2he Atlantic
Month_l_ article). _ The "effective doses" of a drug is the dose
which achieves the desired effect. The "lethal dose" of a drug
is the does which causes death. The "therapeutic ratio," or
ratio of safety_ is the ratio of the effective doses to the
lethal dose. For alcohol, the ratio of safety is approximately
four to ten -- if a person takes four times the effective dose of
alcohol, the dose may be lethal. For barbiturates, the ratio of
safety is approximately three to fifty° There are no documented
cases of death from marijuana overdose anywhere in the worldr but
from animal studies it has been estimated that the ratio of
safety for marijuana is between 20,000 and 40,000_ ___9__, a person
would have to consume 20f000 to 40_000 times the effective dose
to consume a lethal does, a virtual impossibility° In his book,
Against Excess, Associate Professor Mark AoR. Kleiman (Harvard
University) writes:
[M]arijuana does not loom large among
American drug problems in terms of observable
and measurable harm done to users or to
others. Marijuana dealers are not shooting
up the cities, marijuana babies are not
populating the neonatal intensive care wards_
marijuana addicts are not stealing to pay for
their drug habits, marijuana use and
6 See alsoe Exhibit C which is a transcription of a March
9, 1994 Federal Republic of Germany court decision
decrimina!izing personal use of small quantities of marijuana
based on the premise that "there is no objective reason for the
difference in the legal treatment of alcohol and of cannabis
products (hashish and marijuana)°" /__ at 17.
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