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Euphoria and Intraocular Pressure in Man_" 7 Annals of
Ophthalmology 921-923 (1975); M. Perez-Reyes, D. Wagner:
MoE. Walls and KoH. Davist '_Intravenous Administration of
Cannabinoids on intraocular Pressures" The Pharmacology of
Marijuana 829-832 (MoC. Braude and S. Szara eds. 1976); J.C.
Merritt, SoM. McKinnons J.R. Armstrong_ G. Hatem, and L.A.
Reid_ "Oral Delta-9-Tetrahydrocannabinol in Hyperogeneous
Glaucomas, _ 12 Annals of Ophthalmology 947 (1980); K. Green
and M° Roth_ _'Ocular Effects of Topical Administration of
Delta-9-Tetrahydrocannabinol in Man_ '_ I00 Archives of
Ophthalmology 265-267 (1982); and WoM° Jay and K. Green,
_'Multiple-Drop Study of Topically Applied 1% Delta-9_
Tetrahydrocannabinol in Human Eyes_ '_ i01 Archives of
Ophthalmology 591=593 (1983)o
Three studies show very heavy doses of marijuanas taken
for short periods of time, can reduce eye pressure° R.S.
Hepler_ I.Mo Frank, and ToJ. Ungerleider_ _Pupillary
Constriction After Marijuana Smoking: _' 74 American Journal
of Ophthalmology 1185-i190 (1972); RoSo Hepler_ I.Mo Frank,
and Ro Petrus, _Ocular Effects of Marijuana Smokingr" The
Pharmacology of Marijuana 815-824 (1976); and J.Co Merritt,
W.Jo Crawford, P.C. Alexander, A.L° Anduze and S.S. Gelbart,
"Effect of Marijuana on intraocular and Blood Pressure in
Glaucoma_ '" 87 Ophthalmology 222-228 (1980).
Unusually large doses of marijuana were needed in these
three studies to achieve the desired effect. Heavy
i0
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